Long-term gingival disease associated with Alzheimer's disease

Chronic gingival inflammation, or periodontitis, is associated with an increased risk of developing Alzheimer's disease. Chronic periodontitis is the main cause of tooth loss and is also associated with an increase in systemic inflammatory markers. In the study and treatment of Alzheimer's disease, the authors point out that recent studies have shown that chronic periodontitis may lead to decreased thinking ability.


The researchers found no overall association between periodontitis and Alzheimer's disease, but those with 10 or more years of chronic gingival inflammation were more likely to develop Alzheimer's disease than those without periodontitis. The connection between long-term periodontitis and Alzheimer's disease does exist, even through the scientists adjusted some other diseases or living habits that may affect the rapid development of Alzheimer's, such as heart disease, stroke, diabetes and so on.


The team concluded: "Our findings support the notion that infectious diseases associated with low-grade inflammation, such as chronic periodontitis, may play an important role in the pathogenesis of Alzheimer's disease."


However, the researchers also said that these findings may underscore the need to prevent the progression of periodontal and promote national health care.


In fact, it is believed that the link between periodontitis and Alzheimer's disease may be two-way. Currently, based on available scientific evidence, we are unable to determine whether the risk factor is periodontal disease or Alzheimer's disease.


Because periodontitis is a preventable and treatable condition, periodontal patients should be aware of the potential risks of gum infection and the possible systemic effects.